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Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation
Genome packaging is a fundamental process in a viral life cycle and a prime target of antiviral drugs. Herpesviruses use an ATP-driven packaging motor/terminase complex to translocate and cleave concatemeric dsDNA into procapsids but its molecular architecture and mechanism are unknown. We report at...
Autores principales: | Yang, Yunxiang, Yang, Pan, Wang, Nan, Chen, Zhonghao, Su, Dan, Zhou, Z. Hong, Rao, Zihe, Wang, Xiangxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196598/ https://www.ncbi.nlm.nih.gov/pubmed/32328903 http://dx.doi.org/10.1007/s13238-020-00710-0 |
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