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CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway

With its high efficiency for site-specific genome editing and easy manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated protein 9 (CAS9) system has become the most widely used gene editing technology in biomedical research. In addition, significant...

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Detalles Bibliográficos
Autores principales: Xu, Shuxiang, Kim, Jinchul, Tang, Qingshuang, Chen, Qu, Liu, Jingfeng, Xu, Yang, Fu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196600/
https://www.ncbi.nlm.nih.gov/pubmed/32170574
http://dx.doi.org/10.1007/s13238-020-00699-6