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CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway
With its high efficiency for site-specific genome editing and easy manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated protein 9 (CAS9) system has become the most widely used gene editing technology in biomedical research. In addition, significant...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196600/ https://www.ncbi.nlm.nih.gov/pubmed/32170574 http://dx.doi.org/10.1007/s13238-020-00699-6 |