Preclinical Studies of the Off-Target Reactivity of AFP(158)-Specific TCR Engineered T Cells

Autologous T cells engineered with T receptor genes (TCR) are being studied to treat cancers. We have recently identified a panel of mouse TCRs specific for the HLA-A0201/alpha fetoprotein epitope (AFP(158)) complex and have shown that human T cells engineered with these TCR genes (TCR-Ts) can eradi...

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Detalles Bibliográficos
Autores principales: Cai, Lun, Caraballo Galva, Leidy D., Peng, Yibing, Luo, Xiaobing, Zhu, Wei, Yao, Yihong, Ji, Yun, He, Yukai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196607/
https://www.ncbi.nlm.nih.gov/pubmed/32395117
http://dx.doi.org/10.3389/fimmu.2020.00607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196607/
https://www.ncbi.nlm.nih.gov/pubmed/32395117
http://dx.doi.org/10.3389/fimmu.2020.00607

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