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Progressive Changes in Sleep and Its Relations to Amyloid-β Distribution and Learning in Single App Knock-In Mice

Alzheimer’s disease (AD) patients often suffer from sleep disturbances. Alterations in sleep, especially rapid eye movement sleep (REMS), can precede the onset of dementia. To accurately characterize the sleep impairments accompanying AD and their underlying mechanisms using animal models, it is cru...

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Detalles Bibliográficos
Autores principales: Maezono, Sakura Eri B., Kanuka, Mika, Tatsuzawa, Chika, Morita, Miho, Kawano, Taizo, Kashiwagi, Mitsuaki, Nondhalee, Pimpimon, Sakaguchi, Masanori, Saito, Takashi, Saido, Takaomi C., Hayashi, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196722/
https://www.ncbi.nlm.nih.gov/pubmed/32321771
http://dx.doi.org/10.1523/ENEURO.0093-20.2020