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Sennoside A Induces GLP-1 Secretion Through Activation of the ERK1/2 Pathway in L-Cells

PURPOSE: Glucagon-like peptide-1 (GLP-1) is secreted from the intestinal L-cells to stimulate insulin secretion in the blood glucose control. Our previous study indicates that Sennoside A (SA) can increase the plasma GLP-1 level in a mouse model of type 2 diabetes. However, the mechanism of SA activ...

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Detalles Bibliográficos
Autores principales: Ma, Li, Cao, Xinyu, Ye, Xiaotong, Ye, Jianping, Sun, Yongning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196792/
https://www.ncbi.nlm.nih.gov/pubmed/32425572
http://dx.doi.org/10.2147/DMSO.S247251