Cargando…

Sennoside A Induces GLP-1 Secretion Through Activation of the ERK1/2 Pathway in L-Cells

PURPOSE: Glucagon-like peptide-1 (GLP-1) is secreted from the intestinal L-cells to stimulate insulin secretion in the blood glucose control. Our previous study indicates that Sennoside A (SA) can increase the plasma GLP-1 level in a mouse model of type 2 diabetes. However, the mechanism of SA activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Li, Cao, Xinyu, Ye, Xiaotong, Ye, Jianping, Sun, Yongning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196792/ https://www.ncbi.nlm.nih.gov/pubmed/32425572 http://dx.doi.org/10.2147/DMSO.S247251

Ejemplares similares

Regulation of microbiota—GLP1 axis by sennoside A in diet-induced obese mice
por: Le, Jiamei, et al.
Publicado: (2019)

Restoration of GLP-1 secretion by Berberine is associated with protection of colon enterocytes from mitochondrial overheating in diet-induced obese mice
por: Sun, Yongning, et al.
Publicado: (2018)

Aquaporins Alteration Profiles Revealed Different Actions of Senna, Sennosides, and Sennoside A in Diarrhea-Rats
por: Cao, Yixin, et al.
Publicado: (2018)

Transcriptome Analysis of the Inhibitory Effect of Sennoside A on the Metastasis of Hepatocellular Carcinoma Cells
por: Le, Jiamei, et al.
Publicado: (2021)

The Effects and Mechanisms of Sennoside A on Inducing Cytotoxicity, Apoptosis, and Inhibiting Metastasis in Human Chondrosarcoma Cells
por: Le, Jiamei, et al.
Publicado: (2022)

Determination of Total Sennosides and Sennosides A, B, and A(1) in Senna Leaflets, Pods, and Tablets by Two-Dimensional qNMR
por: Çiçek, Serhat Sezai, et al.
Publicado: (2022)

Modulation of HIV-1 capsid multimerization by sennoside A and sennoside B via interaction with the NTD/CTD interface in capsid hexamer
por: Zhang, Da-Wei, et al.
Publicado: (2023)

Pharmacology, Toxicology, and Metabolism of Sennoside A, A Medicinal Plant-Derived Natural Compound
por: Le, Jiamei, et al.
Publicado: (2021)

Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine
por: Wang, Ying, et al.
Publicado: (2021)

Gastroprotective Activities of Sennoside A and Sennoside B via the Up-Regulation of Prostaglandin E(2) and the Inhibition of H(+)/K(+)-ATPase
por: Hwang, In Young, et al.
Publicado: (2015)

GLP-1 Treatment Improves Diabetic Retinopathy by Alleviating Autophagy through GLP-1R-ERK1/2-HDAC6 Signaling Pathway
por: Cai, Xiangsheng, et al.
Publicado: (2017)

Glucolipotoxicity and GLP-1 secretion
por: Hong, Jung-Hee, et al.
Publicado: (2021)

Olfactory Receptor OR51E1 Mediates GLP-1 Secretion in Human and Rodent Enteroendocrine L Cells
por: Han, Ye Eon, et al.
Publicado: (2018)

Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1
por: van Gorkom, B A P, et al.
Publicado: (2002)

The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
por: Hjørne, Anna Pii, et al.
Publicado: (2022)

Promotion of Intestinal Peristalsis by Bifidobacterium spp. Capable of Hydrolysing Sennosides in Mice
por: Matsumoto, Mitsuharu, et al.
Publicado: (2012)

Removal of Duodenum Elicits GLP-1 Secretion
por: Muscogiuri, Giovanna, et al.
Publicado: (2013)

Activation of TLRs Triggers GLP-1 Secretion in Mice
por: Lebrun, Lorène J., et al.
Publicado: (2023)

Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits
por: Wei, Zhonghong, et al.
Publicado: (2020)

NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion
por: Herz, Hussein, et al.
Publicado: (2021)

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
por: Ma, Xiaoxuan, et al.
Publicado: (2021)

Sennoside A drug capped biogenic fabrication of silver nanoparticles and their antibacterial and antifungal activities
por: Al-Ghamdi, Areej Dhawi, et al.
Publicado: (2020)

The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
por: Ørgaard, Anne, et al.
Publicado: (2017)

Mechanisms Controlling Glucose-Induced GLP-1 Secretion in Human Small Intestine
por: Sun, Emily W., et al.
Publicado: (2017)

Response Surface Methodology (RSM)-Based Optimization of Ultrasound-Assisted Extraction of Sennoside A, Sennoside B, Aloe-Emodin, Emodin, and Chrysophanol from Senna alexandrina (Aerial Parts): HPLC-UV and Antioxidant Analysis
por: Alam, Perwez, et al.
Publicado: (2022)

Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion
por: Ahlkvist, L, et al.
Publicado: (2013)

Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture
por: Goldspink, Deborah A., et al.
Publicado: (2020)

Induction of Energy Expenditure by Sitagliptin Is Dependent on GLP-1 Receptor
por: Goldsmith, Felicia, et al.
Publicado: (2015)

Galanin inhibits GLP‐1 and GIP secretion via the GAL(1) receptor in enteroendocrine L and K cells
por: Psichas, Arianna, et al.
Publicado: (2016)

Sennoside A inhibits quorum sensing system to attenuate its regulated virulence and pathogenicity via targeting LasR in Pseudomonas aeruginosa
por: Han, Xiaofeng, et al.
Publicado: (2022)

Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10
por: Schwetz, Tara A., et al.
Publicado: (2014)

Circadian secretion rhythm of GLP-1 and its influencing factors
por: Liu, Chuanfeng, et al.
Publicado: (2022)

Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs
por: Drzazga, Anna, et al.
Publicado: (2021)

MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway
por: Wang, Yifen, et al.
Publicado: (2022)

GLP-1 Receptor Agonists Induce Growth Hormone Secretion in Healthy Volunteers
por: Heinla, Keiu, et al.
Publicado: (2023)

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells
por: Hodge, Daryl, et al.
Publicado: (2016)

Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-Cells
por: Mooli, Raja Gopal Reddy, et al.
Publicado: (2021)

GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway
por: Zhu, Tao, et al.
Publicado: (2018)

CCK‐1 and CCK‐2 receptor agonism do not stimulate GLP‐1 and neurotensin secretion in the isolated perfused rat small intestine or GLP‐1 and PYY secretion in the rat colon
por: Modvig, Ida M., et al.
Publicado: (2020)

Synergistic effects of metformin with liraglutide against endothelial dysfunction through GLP-1 receptor and PKA signalling pathway
por: Ke, Jing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ovhi84lucmmfa8ofrt9bcmqhin