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JNK-dependent intestinal barrier failure disrupts host–microbe homeostasis during tumorigenesis

In all animals, the intestinal epithelium forms a tight barrier to the environment. The epithelium regulates the absorption of nutrients, mounts immune responses, and prevents systemic infections. Here, we investigate the consequences of tumorigenesis on the microbiome using a Drosophila intestinal...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196803/
https://www.ncbi.nlm.nih.gov/pubmed/32277031
http://dx.doi.org/10.1073/pnas.1913976117