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JNK-dependent intestinal barrier failure disrupts host–microbe homeostasis during tumorigenesis
In all animals, the intestinal epithelium forms a tight barrier to the environment. The epithelium regulates the absorption of nutrients, mounts immune responses, and prevents systemic infections. Here, we investigate the consequences of tumorigenesis on the microbiome using a Drosophila intestinal...
Autores principales: | Zhou, Jun, Boutros, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196803/ https://www.ncbi.nlm.nih.gov/pubmed/32277031 http://dx.doi.org/10.1073/pnas.1913976117 |
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