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Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling

Inositol diphosphates (PP-IPs), also known as inositol pyrophosphates, are high-energy cellular signaling codes involved in nutrient and regulatory responses. We report that the evolutionarily conserved gene product, Vip1, possesses autonomous kinase and pyrophosphatase domains capable of synthesis...

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Detalles Bibliográficos
Autores principales: Dollins, D. Eric, Bai, Wenli, Fridy, Peter C., Otto, James C., Neubauer, Julie L., Gattis, Samuel G., Mehta, Kavi P. M., York, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196807/
https://www.ncbi.nlm.nih.gov/pubmed/32303658
http://dx.doi.org/10.1073/pnas.1908875117