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Noninvasive hippocampal blood−brain barrier opening in Alzheimer’s disease with focused ultrasound
The blood–brain barrier (BBB) presents a significant challenge for treating brain disorders. The hippocampus is a key target for novel therapeutics, playing an important role in Alzheimer’s disease (AD), epilepsy, and depression. Preclinical studies have shown that magnetic resonance (MR)-guided low...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196825/ https://www.ncbi.nlm.nih.gov/pubmed/32284421 http://dx.doi.org/10.1073/pnas.2002571117 |