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Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Translation depends on messenger RNA (mRNA)-specific initiation, elongation, and termination rates. While translation elongation is well studied in bacteria and yeast, less is known in higher eukaryotes. Here we combined ribosome and transfer RNA (tRNA) profiling to investigate the relations between...

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Detalles Bibliográficos
Autores principales: Gobet, Cédric, Weger, Benjamin Dieter, Marquis, Julien, Martin, Eva, Neelagandan, Nagammal, Gachon, Frédéric, Naef, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196831/
https://www.ncbi.nlm.nih.gov/pubmed/32295881
http://dx.doi.org/10.1073/pnas.1918145117