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HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

Structural and functional studies of HIV envelope glycoprotein (Env) as a transmembrane protein have long been complicated by challenges associated with inherent flexibility of the molecule and the membrane-embedded hydrophobic regions. Here, we present approaches for incorporating full-length, wild...

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Detalles Bibliográficos
Autores principales: Rantalainen, Kimmo, Berndsen, Zachary T., Antanasijevic, Aleksandar, Schiffner, Torben, Zhang, Xi, Lee, Wen-Hsin, Torres, Jonathan L., Zhang, Lei, Irimia, Adriana, Copps, Jeffrey, Zhou, Kenneth H., Kwon, Young D., Law, William H., Schramm, Chaim A., Verardi, Raffaello, Krebs, Shelly J., Kwong, Peter D., Doria-Rose, Nicole A., Wilson, Ian A., Zwick, Michael B., Yates, John R., Schief, William R., Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196886/
https://www.ncbi.nlm.nih.gov/pubmed/32348769
http://dx.doi.org/10.1016/j.celrep.2020.107583