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Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy

Advances in electron microscopy including improved imaging techniques and state-of-the-art detectors facilitate imaging of larger tissue volumes with electron microscopic resolution. In combination with genetic tools for the generation of mouse mutants this allows assessing the three-dimensional (3D...

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Detalles Bibliográficos
Autores principales: Steyer, Anna M., Ruhwedel, Torben, Nardis, Christos, Werner, Hauke B., Nave, Klaus-Armin, Möbius, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196930/
https://www.ncbi.nlm.nih.gov/pubmed/32156581
http://dx.doi.org/10.1016/j.jsb.2020.107492