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Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy
Advances in electron microscopy including improved imaging techniques and state-of-the-art detectors facilitate imaging of larger tissue volumes with electron microscopic resolution. In combination with genetic tools for the generation of mouse mutants this allows assessing the three-dimensional (3D...
Autores principales: | Steyer, Anna M., Ruhwedel, Torben, Nardis, Christos, Werner, Hauke B., Nave, Klaus-Armin, Möbius, Wiebke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196930/ https://www.ncbi.nlm.nih.gov/pubmed/32156581 http://dx.doi.org/10.1016/j.jsb.2020.107492 |
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