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Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway

The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a redox-sensitive transcription factor controlling a variety of downstream antioxidant and cytodefensive genes. Nrf2 has a powerful...

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Detalles Bibliográficos
Autores principales: Hassanein, Emad H. M., Sayed, Ahmed M., Hussein, Omnia E., Mahmoud, Ayman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196981/
https://www.ncbi.nlm.nih.gov/pubmed/32377290
http://dx.doi.org/10.1155/2020/1675957