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Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a redox-sensitive transcription factor controlling a variety of downstream antioxidant and cytodefensive genes. Nrf2 has a powerful...
Autores principales: | Hassanein, Emad H. M., Sayed, Ahmed M., Hussein, Omnia E., Mahmoud, Ayman M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196981/ https://www.ncbi.nlm.nih.gov/pubmed/32377290 http://dx.doi.org/10.1155/2020/1675957 |
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