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Stratified Test Alleviates Batch Effects in Single-Cell Data

Analyzing single-cell sequencing data across batches is challenging. We find that the Van Elteren test, a stratified version of Wilcoxon rank-sum test, elegantly mitigates the problem. We also modified the common language effect size to supplement this test, further improving its utility. On both si...

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Detalles Bibliográficos
Autores principales: Liang, Shaoheng, Liang, Qingnan, Chen, Rui, Chen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197071/
http://dx.doi.org/10.1007/978-3-030-42266-0_13