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The role of baseline BLyS levels and type 1 interferon-inducible gene signature status in determining belimumab response in systemic lupus erythematosus: a post hoc meta-analysis

BACKGROUND: Elevated B lymphocyte stimulator (BLyS) levels in patients with systemic lupus erythematosus (SLE) correlate positively with disease activity; BLyS expression is directly linked to interferon (IFN) pathway activation. This post hoc meta-analysis of BLISS-52 and BLISS-76 explored the rela...

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Detalles Bibliográficos
Autores principales: Wilkinson, Christel, Henderson, Robert B., Jones-Leone, Angela R., Flint, Shaun M., Lennon, Mark, Levy, Roger A., Ji, Beulah, Bass, Damon L., Roth, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197114/
https://www.ncbi.nlm.nih.gov/pubmed/32366280
http://dx.doi.org/10.1186/s13075-020-02177-0