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Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia

BACKGROUND: We used bioinformatic tools to dichotomize 157 non-M3 AML patients from the TCGA dataset based on the presence or absence of TP53 mutations, and screened out a key gene related to TP53 mutation for future analysis. METHODS: DEGs were analyzed by R package “DESeq2” and then run GSEA, GO e...

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Detalles Bibliográficos
Autores principales: Gu, Siyu, Zi, Jie, Han, Qi, Song, Chunhua, Ge, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197135/
https://www.ncbi.nlm.nih.gov/pubmed/32390761
http://dx.doi.org/10.1186/s12935-020-01213-y