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Differential gene methylation and expression of HOX transcription factor family in orbitofacial neurofibroma

Although most commonly benign, neurofibromas (NFs) can have devastating functional and cosmetic effects in addition to the possibility of malignant transformation. In orbitofacial neurofibromatosis type 1, NFs may cause progressive, disfiguring tumors of the lid, brow, temple, face and orbit. The pu...

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Detalles Bibliográficos
Autores principales: Arnold, Antje, Imada, Eddie Luidy, Zhang, Lisa, Edward, Deepak P., Marchionni, Luigi, Rodriguez, Fausto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197183/
https://www.ncbi.nlm.nih.gov/pubmed/32366326
http://dx.doi.org/10.1186/s40478-020-00940-7