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Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis

Dmrt5 (Dmrta2) and Dmrt3 are key regulators of cortical patterning and progenitor proliferation and differentiation. In this study, we show an altered apical to intermediate progenitor transition, with a delay in SP neurogenesis and premature birth of Ctip2(+) cortical neurons in Dmrt5(−/−) mice. In...

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Detalles Bibliográficos
Autores principales: Ratié, Leslie, Desmaris, Elodie, García-Moreno, Fernando, Hoerder-Suabedissen, Anna, Kelman, Alexandra, Theil, Thomas, Bellefroid, Eric J, Molnár, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197206/
https://www.ncbi.nlm.nih.gov/pubmed/31845734
http://dx.doi.org/10.1093/cercor/bhz310