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Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis
Dmrt5 (Dmrta2) and Dmrt3 are key regulators of cortical patterning and progenitor proliferation and differentiation. In this study, we show an altered apical to intermediate progenitor transition, with a delay in SP neurogenesis and premature birth of Ctip2(+) cortical neurons in Dmrt5(−/−) mice. In...
Autores principales: | Ratié, Leslie, Desmaris, Elodie, García-Moreno, Fernando, Hoerder-Suabedissen, Anna, Kelman, Alexandra, Theil, Thomas, Bellefroid, Eric J, Molnár, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197206/ https://www.ncbi.nlm.nih.gov/pubmed/31845734 http://dx.doi.org/10.1093/cercor/bhz310 |
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