A Mouse Model of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Parkinson Disease Shows that 2-Aminoquinoline Targets JNK Phosphorylation

BACKGROUND: The pathological features of Parkinson disease (PD) include motor deficits, glial cell activation, and neuroinflammation. The neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), has an oxidation product, 1-methyl-4-phenylpyridinium ion (MPP+). This study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Zhu, Meie, Gong, Daokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197228/
https://www.ncbi.nlm.nih.gov/pubmed/32333598
http://dx.doi.org/10.12659/MSM.920989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197228/
https://www.ncbi.nlm.nih.gov/pubmed/32333598
http://dx.doi.org/10.12659/MSM.920989

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