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Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2

Excessive vascular smooth muscle cell (VSMC) proliferation contributes to the development of atherosclerosis and restenosis. Furthermore, apoptosis of VSMCs accelerates plaque rupture in the atherosclerotic vessels. Therefore, a strategy that regulates both VSMC proliferation and apoptosis is essent...

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Detalles Bibliográficos
Autores principales: Lee, Seunghyeong, Byun, Jun-Kyu, Park, Mihyang, Woo Kim, Sung, Lee, Sungwoo, Kim, Jung-Guk, Lee, In-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197251/
https://www.ncbi.nlm.nih.gov/pubmed/32373191
http://dx.doi.org/10.3892/etm.2020.8638