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Embryo integrity regulates maternal proteostasis and stress resilience

The proteostasis network is regulated by transcellular communication to promote health and fitness in metazoans. In Caenorhabditis elegans, signals from the germline initiate the decline of proteostasis and repression of cell stress responses at reproductive maturity, indicating that commitment to r...

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Detalles Bibliográficos
Autores principales: Sala, Ambre J., Bott, Laura C., Brielmann, Renee M., Morimoto, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197353/
https://www.ncbi.nlm.nih.gov/pubmed/32217667
http://dx.doi.org/10.1101/gad.335422.119