Enhanced genome editing in human iPSCs with CRISPR-CAS9 by co-targeting ATP1a1

Genome editing in human induced pluripotent stem cells (iPSCs) provides the potential for disease modeling and cell therapy. By generating iPSCs with specific mutations, researchers can differentiate the modified cells to their lineage of interest for further investigation. However, the low efficien...

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Detalles Bibliográficos
Autores principales: Liu, Jui-Tung, Corbett, James L., Heslop, James A., Duncan, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197401/
https://www.ncbi.nlm.nih.gov/pubmed/32391204
http://dx.doi.org/10.7717/peerj.9060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197401/
https://www.ncbi.nlm.nih.gov/pubmed/32391204
http://dx.doi.org/10.7717/peerj.9060

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