Cargando…
Enhanced genome editing in human iPSCs with CRISPR-CAS9 by co-targeting ATP1a1
Genome editing in human induced pluripotent stem cells (iPSCs) provides the potential for disease modeling and cell therapy. By generating iPSCs with specific mutations, researchers can differentiate the modified cells to their lineage of interest for further investigation. However, the low efficien...
Autores principales: | Liu, Jui-Tung, Corbett, James L., Heslop, James A., Duncan, Stephen A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197401/ https://www.ncbi.nlm.nih.gov/pubmed/32391204 http://dx.doi.org/10.7717/peerj.9060 |
Ejemplares similares
-
Human iPSCs and Genome Editing Technologies for Precision Cardiovascular Tissue Engineering
por: Gähwiler, Eric K. N., et al.
Publicado: (2021) -
Rapid genome editing by CRISPR-Cas9-POLD3 fusion
por: Reint, Ganna, et al.
Publicado: (2021) -
Pannexin 1 Influences Lineage Specification of Human iPSCs
por: Noort, Rebecca J., et al.
Publicado: (2021) -
Correction of F8 intron 1 inversion in hemophilia A patient-specific iPSCs by CRISPR/Cas9 mediated gene editing
por: Hu, Zhiqing, et al.
Publicado: (2023) -
Opportunities for CRISPR/Cas9 Gene Editing in Retinal Regeneration Research
por: Campbell, Leah J., et al.
Publicado: (2017)