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Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo

Antigen capturing at the periphery is one of the earliest, crucial functions of antigen-presenting cells (APCs) to initiate immune responses. Langerhans cells (LCs), the epidermal APCs migrate to draining lymph nodes (DLNs) upon acquiring antigens. An arsenal of endocytic molecules is available to t...

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Detalles Bibliográficos
Autores principales: Becerril-García, Miguel Angel, Yam-Puc, Juan Carlos, Maqueda-Alfaro, Raúl, Beristain-Covarrubias, Nonantzin, Heras-Chavarría, Monica, Gallegos-Hernández, Isis Amara, Calderón-Amador, Juana, Munguía-Fuentes, Rosario, Donis-Maturano, Luis, Flores-Langarica, Adriana, Flores-Romo, Leopoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197463/
https://www.ncbi.nlm.nih.gov/pubmed/32395120
http://dx.doi.org/10.3389/fimmu.2020.00744