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Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo
Antigen capturing at the periphery is one of the earliest, crucial functions of antigen-presenting cells (APCs) to initiate immune responses. Langerhans cells (LCs), the epidermal APCs migrate to draining lymph nodes (DLNs) upon acquiring antigens. An arsenal of endocytic molecules is available to t...
Autores principales: | Becerril-García, Miguel Angel, Yam-Puc, Juan Carlos, Maqueda-Alfaro, Raúl, Beristain-Covarrubias, Nonantzin, Heras-Chavarría, Monica, Gallegos-Hernández, Isis Amara, Calderón-Amador, Juana, Munguía-Fuentes, Rosario, Donis-Maturano, Luis, Flores-Langarica, Adriana, Flores-Romo, Leopoldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197463/ https://www.ncbi.nlm.nih.gov/pubmed/32395120 http://dx.doi.org/10.3389/fimmu.2020.00744 |
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