Cargando…

RETrace: simultaneous retrospective lineage tracing and methylation profiling of single cells

Retrospective lineage tracing harnesses naturally occurring mutations in cells to elucidate single cell development. Common single-cell phylogenetic fate mapping methods have utilized highly mutable microsatellite loci found within the human genome. Such methods were limited by the introduction of i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Christopher Jen-Yue, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197472/
https://www.ncbi.nlm.nih.gov/pubmed/32127417
http://dx.doi.org/10.1101/gr.255851.119