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Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

Cellular heterogeneity in gene expression is driven by cellular processes, such as cell cycle and cell-type identity, and cellular environment such as spatial location. The cell cycle, in particular, is thought to be a key driver of cell-to-cell heterogeneity in gene expression, even in otherwise ho...

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Detalles Bibliográficos
Autores principales: Hsiao, Chiaowen Joyce, Tung, PoYuan, Blischak, John D., Burnett, Jonathan E., Barr, Kenneth A., Dey, Kushal K., Stephens, Matthew, Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197478/
https://www.ncbi.nlm.nih.gov/pubmed/32312741
http://dx.doi.org/10.1101/gr.247759.118