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Redundant and specific roles of cohesin STAG subunits in chromatin looping and transcriptional control

Cohesin is a ring-shaped multiprotein complex that is crucial for 3D genome organization and transcriptional regulation during differentiation and development. It also confers sister chromatid cohesion and facilitates DNA damage repair. Besides its core subunits SMC3, SMC1A, and RAD21, cohesin in so...

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Detalles Bibliográficos
Autores principales: Casa, Valentina, Moronta Gines, Macarena, Gade Gusmao, Eduardo, Slotman, Johan A., Zirkel, Anne, Josipovic, Natasa, Oole, Edwin, van IJcken, Wilfred F.J., Houtsmuller, Adriaan B., Papantonis, Argyris, Wendt, Kerstin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197483/
https://www.ncbi.nlm.nih.gov/pubmed/32253279
http://dx.doi.org/10.1101/gr.253211.119