Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects

Transgenic Cre-recombinase expressing mouse lines are widely used to express fluorescent proteins and opto-/chemogenetic actuators, making them a cornerstone of modern neuroscience. The investigation of interneurons in particular has benefitted from the ability to genetically target specific cell ty...

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Detalles Bibliográficos
Autores principales: Müller-Komorowska, Daniel, Opitz, Thoralf, Elzoheiry, Shehabeldin, Schweizer, Michaela, Ambrad Giovannetti, Eleonora, Beck, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197702/
https://www.ncbi.nlm.nih.gov/pubmed/32395103
http://dx.doi.org/10.3389/fncir.2020.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197702/
https://www.ncbi.nlm.nih.gov/pubmed/32395103
http://dx.doi.org/10.3389/fncir.2020.00016

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