Cargando…

Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NFκB-mediated inflammation in IUGR mice

Infants with intrauterine growth retardation (IUGR) have a high risk of developing bronchial asthma in childhood, but the underlying mechanisms remain unclear. This study aimed to disclose the role of vascular non-inflammatory molecule 1 (vannin-1, encoded by the Vnn1 gene) and its downstream signal...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Yan, Wei, Hongling, Xiao, Xiumei, Chen, Zekun, Liu, Hui, Tong, Xiaomei, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197710/
https://www.ncbi.nlm.nih.gov/pubmed/32139393
http://dx.doi.org/10.1242/bio.049106