Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis

Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new drug combinations to trigger defatting in three human culture models, primary hepatocytes with induced steatosis, primary hepatocytes isolat...

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Detalles Bibliográficos
Autores principales: Aoudjehane, Lynda, Gautheron, Jérémie, Le Goff, Wilfried, Goumard, Claire, Gilaizeau, Julia, Nget, Chan Sonavine, Savier, Eric, Atif, Muhammad, Lesnik, Philippe, Morichon, Romain, Chrétien, Yves, Calmus, Yvon, Scatton, Olivier, Housset, Chantal, Conti, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197711/
https://www.ncbi.nlm.nih.gov/pubmed/32094147
http://dx.doi.org/10.1242/dmm.042663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197711/
https://www.ncbi.nlm.nih.gov/pubmed/32094147
http://dx.doi.org/10.1242/dmm.042663

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