Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration

Runx1 is a transcription factor that plays a key role in determining the proliferative and differential state of multiple cell types, during both development and adulthood. Here, we report how Runx1 is specifically upregulated at the injury site during zebrafish heart regeneration, and that absence...

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Detalles Bibliográficos
Autores principales: Koth, Jana, Wang, Xiaonan, Killen, Abigail C., Stockdale, William T., Potts, Helen G., Jefferson, Andrew, Bonkhofer, Florian, Riley, Paul R., Patient, Roger K., Göttgens, Berthold, Mommersteeg, Mathilda T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197712/
https://www.ncbi.nlm.nih.gov/pubmed/32341028
http://dx.doi.org/10.1242/dev.186569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197712/
https://www.ncbi.nlm.nih.gov/pubmed/32341028
http://dx.doi.org/10.1242/dev.186569

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