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Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis

Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling cooperates with Tbx transcription factors to promote dorsal mesoderm formation, but their role in myogenesis has been unclear. Using zebrafish, we show that dorsally derived...

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Detalles Bibliográficos
Autores principales: Osborn, Daniel P. S., Li, Kuoyu, Cutty, Stephen J., Nelson, Andrew C., Wardle, Fiona C., Hinits, Yaniv, Hughes, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197714/
https://www.ncbi.nlm.nih.gov/pubmed/32345657
http://dx.doi.org/10.1242/dev.184689