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Nucleolar stress in Drosophila neuroblasts, a model for human ribosomopathies

Different stem cells or progenitor cells display variable threshold requirements for functional ribosomes. This is particularly true for several human ribosomopathies in which select embryonic neural crest cells or adult bone marrow stem cells, but not others, show lethality due to failures in ribos...

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Detalles Bibliográficos
Autores principales: Baral, Sonu Shrestha, Lieux, Molly E., DiMario, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197718/
https://www.ncbi.nlm.nih.gov/pubmed/32184230
http://dx.doi.org/10.1242/bio.046565