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Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

Human herpesviruses 6A and 6B (HHV-6A/B) are unique among human herpesviruses in their ability to integrate their genome into host chromosomes. Viral integration occurs at the ends of chromosomes within the host telomeres. The ends of the HHV-6A/B genomes contain telomeric repeats that facilitate th...

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Detalles Bibliográficos
Autores principales: Gilbert-Girard, Shella, Gravel, Annie, Collin, Vanessa, Wight, Darren J., Kaufer, Benedikt B., Lazzerini-Denchi, Eros, Flamand, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197865/
https://www.ncbi.nlm.nih.gov/pubmed/32320442
http://dx.doi.org/10.1371/journal.ppat.1008496