Rapid identification of human mast cell degranulation regulators using functional genomics coupled to high-resolution confocal microscopy

Targeted functional genomics represents a powerful approach for studying gene function in vivo and in vitro. However, its application to gene expression studies in human mast cells has been hampered by low yields of human mast cell cultures and their poor transfection efficiency. We developed an ima...

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Detalles Bibliográficos
Autores principales: Folkerts, Jelle, Gaudenzio, Nicolas, Maurer, Marcus, Hendriks, Rudi W., Stadhouders, Ralph, Tam, See-Ying, Galli, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197894/
https://www.ncbi.nlm.nih.gov/pubmed/32060492
http://dx.doi.org/10.1038/s41596-019-0288-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197894/
https://www.ncbi.nlm.nih.gov/pubmed/32060492
http://dx.doi.org/10.1038/s41596-019-0288-6

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