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MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib

PURPOSE: Sorafenib has revolutionized treatment of hepatocellular carcinoma (HCC), but its efficacy is limited by drug resistance. Autophagy is the process by which cellular components are transported to lysosomes for degradation, which promotes energy production and production of macromolecular pre...

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Detalles Bibliográficos
Autores principales: Yang, Shuo, Wang, Minggang, Yang, Liang, Li, Yan, Ma, Yingbo, Peng, Xueqiang, Li, Xinyu, Li, Bowen, Jin, Hongyuan, Li, Hangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197942/
https://www.ncbi.nlm.nih.gov/pubmed/32431510
http://dx.doi.org/10.2147/OTT.S247655