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Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges
Signal transducers and activators of transcription 3 (STAT-3) is a transcription factor that regulates the gene expression of several target genes. These factors are activated by the binding of cytokines and growth factors with STAT-3 specific receptors on cell membrane. Few years ago, STAT-3 was co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198026/ https://www.ncbi.nlm.nih.gov/pubmed/32167126 http://dx.doi.org/10.1590/1678-4685-GMB-2018-0160 |