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Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges

Signal transducers and activators of transcription 3 (STAT-3) is a transcription factor that regulates the gene expression of several target genes. These factors are activated by the binding of cytokines and growth factors with STAT-3 specific receptors on cell membrane. Few years ago, STAT-3 was co...

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Detalles Bibliográficos
Autores principales:	Arshad, Sundas, Naveed, Muhammad, Ullia, Mahad, Javed, Khadija, Butt, Ayesha, Khawar, Masooma, Amjad, Fazeeha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2020
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198026/ https://www.ncbi.nlm.nih.gov/pubmed/32167126 http://dx.doi.org/10.1590/1678-4685-GMB-2018-0160

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