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Transcriptional regulators and regulatory pathways involved in prostate gland adaptation to a hypoandrogen environment
Anti-androgen therapies, including orchiectomy, are effective at promoting prostate cancer remission, but are followed by progression to the more aggressive castration-resistant prostate cancer (CRPC). Castration promotes gland and tumor shrinkage. However, prostate adaptation to androgen deprivatio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198032/ https://www.ncbi.nlm.nih.gov/pubmed/32159609 http://dx.doi.org/10.1590/1678-4685-GMB-2018-0362 |