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Transcriptional regulators and regulatory pathways involved in prostate gland adaptation to a hypoandrogen environment

Anti-androgen therapies, including orchiectomy, are effective at promoting prostate cancer remission, but are followed by progression to the more aggressive castration-resistant prostate cancer (CRPC). Castration promotes gland and tumor shrinkage. However, prostate adaptation to androgen deprivatio...

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Detalles Bibliográficos
Autores principales: Nishan, Umar, da Rosa-Ribeiro, Rafaela, Damas-Souza, Danilo Marchete, Barbosa, Guilherme Oliveira, Carvalho, Hernandes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198032/
https://www.ncbi.nlm.nih.gov/pubmed/32159609
http://dx.doi.org/10.1590/1678-4685-GMB-2018-0362