Cargando…
DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance
Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five years or more. Several pieces of evidence have suggested that the DNA damage...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198033/ https://www.ncbi.nlm.nih.gov/pubmed/31930277 http://dx.doi.org/10.1590/1678-4685-GMB-2019-0066 |