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DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance

Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five years or more. Several pieces of evidence have suggested that the DNA damage...

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Detalles Bibliográficos
Autores principales: de Sousa, Juliana Ferreira, Serafim, Rodolfo Bortolozo, de Freitas, Laura Marise, Fontana, Carla Raquel, Valente, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198033/
https://www.ncbi.nlm.nih.gov/pubmed/31930277
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0066