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Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases

Long-chain fatty acyl CoA synthetases (ACSLs) activate fatty acids by CoA addition thus facilitating their intracellular metabolism. Dysregulated ACSL expression features in several cancers and can affect processes such as ferroptosis, fatty acid β-oxidation, prostaglandin biosynthesis, steroidogene...

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Detalles Bibliográficos
Autores principales: Ndiaye, Haarith, Liu, Jorlin Y., Hall, Andrew, Minogue, Shane, Morgan, Marsha Y., Waugh, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198044/
https://www.ncbi.nlm.nih.gov/pubmed/32286604
http://dx.doi.org/10.1042/BSR20200219