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Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-Binding Motif

Replication initiation in eukaryotic cells occurs asynchronously throughout S phase, yielding early- and late-replicating regions of the genome, a process known as replication timing (RT). RT changes during development to ensure accurate genome duplication and maintain genome stability. To understan...

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Detalles Bibliográficos
Autores principales: Armstrong, Robin L., Das, Souradip, Hill, Christina A., Duronio, Robert J., Nordman, Jared T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198277/
https://www.ncbi.nlm.nih.gov/pubmed/32144132
http://dx.doi.org/10.1534/genetics.120.303155