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Increased O-GlcNAcylation rapidly decreases GABA(A)R currents in hippocampus but depresses neuronal output
O-GlcNAcylation, a post-translational modification involving O-linkage of β-N-acetylglucosamine to Ser/Thr residues on target proteins, is increasingly recognized as a critical regulator of synaptic function. Enzymes that catalyze O-GlcNAcylation are found at both presynaptic and postsynaptic sites,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198489/ https://www.ncbi.nlm.nih.gov/pubmed/32366857 http://dx.doi.org/10.1038/s41598-020-63188-0 |