Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

Death-associated protein kinase 1 (DAPK1, DAPk, DAPK) is known for its involvement in apoptosis and autophagy-associated cell death. Here, we identified an unexpected function of DAPK1 in suppressing necroptosis. DAPK1-deficiency renders macrophages and dendritic cells susceptible to necroptotic dea...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yung-Hsuan, Chou, Ting-Fang, Young, Leslie, Hsieh, Fu-Yi, Pan, Hsuan-Yin, Mo, Shu-Ting, Brown, Shani Bialik, Chen, Ruey-Hwa, Kimchi, Adi, Lai, Ming-Zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198492/
https://www.ncbi.nlm.nih.gov/pubmed/32366830
http://dx.doi.org/10.1038/s41419-020-2534-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198492/
https://www.ncbi.nlm.nih.gov/pubmed/32366830
http://dx.doi.org/10.1038/s41419-020-2534-9

Ejemplares similares