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TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating

Transition fibers (TFs) regulate cilia gating and make the primary cilium a distinct functional entity. However, molecular insights into the biogenesis of a functional cilia gate remain elusive. In a forward genetic screen in Caenorhabditis elegans, we uncover that TALP-3, a homolog of the Joubert s...

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Detalles Bibliográficos
Autores principales: Yan, Hao, Chen, Chuan, Chen, Huicheng, Hong, Hui, Huang, Yan, Ling, Kun, Hu, Jinghua, Wei, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198521/
https://www.ncbi.nlm.nih.gov/pubmed/32366837
http://dx.doi.org/10.1038/s41467-020-16042-w